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From physics we know that materials consist of little pieces, the atoms. Together they build the molecules. Their shape causes the structure of the material. For example we know the structure of cristallised salt (NaCl). Because atoms are very tiny (1nm to 1Å) they are not visible to the naked eye nor by the custom microscopes. They are too little to reflect visible arrays of light. That's why we never can see atoms by any optical lens.
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